Fang Li Selected Research

radix ophiopogonis drug combination radix ginseng fructus schizandrae (Shen Mai)

1/2022	YiQiFuMai lyophilized injection attenuates cerebral ischemic injury with inhibition of neuronal autophagy through intervention in the NMMHC IIA-actin-ATG9A interaction.
1/2021	Mechanisms dissection of the combination GRS derived from ShengMai preparations for the treatment of myocardial ischemia/reperfusion injury.
1/2020	The Traditional Chinese Medicine Compound, GRS, Alleviates Blood-Brain Barrier Dysfunction.
1/2019	YiQiFuMai Powder Injection Attenuates Coronary Artery Ligation-Induced Heart Failure Through Improving Mitochondrial Function via Regulating ROS Generation and CaMKII Signaling Pathways.
1/2018	A Strategy for Optimizing the Combination of Active Components Based on Chinese Medicinal Formula Sheng-Mai-San for Myocardial Ischemia.
4/2017	YiQiFuMai Powder Injection attenuates coronary artery ligation-induced myocardial remodeling and heart failure through modulating MAPKs signaling pathway.
1/2017	An integrated shotgun proteomics and bioinformatics approach for analysis of brain proteins from MCAO model using serial affinity chromatograph with four active ingredients from Shengmai preparations as ligands.
11/2016	Cardioprotection by combination of three compounds from ShengMai preparations in mice with myocardial ischemia/reperfusion injury through AMPK activation-mediated mitochondrial fission.
5/2016	YiQiFuMai Powder Injection ameliorates the oxygen-glucose deprivation-induced brain microvascular endothelial barrier dysfunction associated with the NF-κB and ROCK1/MLC signaling pathways.
11/2015	An integrated pathway interaction network for the combination of four effective compounds from ShengMai preparations in the treatment of cardio-cerebral ischemic diseases.

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Fang Li Research Topics

Disease

277	Neoplasms (Cancer) 12/2022 - 04/2002
92	Infections 02/2022 - 09/2005
69	Inflammation (Inflammations) 10/2022 - 03/2005
50	Neoplasm Metastasis (Metastasis) 01/2022 - 01/2005
40	Breast Neoplasms (Breast Cancer) 02/2022 - 03/2004
33	COVID-19 01/2022 - 01/2020
32	Carcinogenesis 04/2022 - 05/2004
30	Lung Neoplasms (Lung Cancer) 12/2022 - 10/2007
29	Body Weight (Weight, Body) 01/2022 - 01/2010
28	Fibrosis (Cirrhosis) 08/2022 - 08/2010
24	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 06/2021 - 04/2014
21	Stroke (Strokes) 01/2022 - 06/2010
20	Hepatocellular Carcinoma (Hepatoma) 01/2022 - 10/2013
20	Hypoxia (Hypoxemia) 01/2022 - 11/2004
19	Stomach Neoplasms (Stomach Cancer) 01/2022 - 05/2008
18	Carcinoma (Carcinomatosis) 01/2022 - 10/2005
18	Pain (Aches) 01/2022 - 07/2010
17	Myocardial Infarction 01/2022 - 04/2007
16	Alzheimer Disease (Alzheimer's Disease) 08/2022 - 09/2005
16	Cardiovascular Diseases (Cardiovascular Disease) 03/2022 - 06/2006
15	Colorectal Neoplasms (Colorectal Cancer) 11/2021 - 12/2007
15	Hypertension (High Blood Pressure) 05/2019 - 06/2010
14	Uterine Cervical Neoplasms (Cancer of the Cervix) 05/2022 - 08/2014
14	Disease Progression 01/2022 - 06/2013
13	Brain Ischemia (Cerebral Ischemia) 08/2022 - 09/2012
13	Ischemic Stroke 08/2022 - 06/2010
13	Insulin Resistance 01/2022 - 08/2010
13	Ovarian Neoplasms (Ovarian Cancer) 09/2021 - 03/2004
12	Parkinson Disease (Parkinson's Disease) 05/2022 - 02/2012
12	Wounds and Injuries (Trauma) 04/2022 - 03/2007
12	Prostatic Neoplasms (Prostate Cancer) 12/2021 - 10/2012
12	Colonic Neoplasms (Colon Cancer) 01/2021 - 01/2011
11	Heart Failure 08/2022 - 01/2017
11	Sepsis (Septicemia) 06/2022 - 01/2015
11	Myocardial Ischemia (Ischemic Heart Diseases) 03/2022 - 01/2014
11	Cognitive Dysfunction 01/2022 - 11/2014
11	Type 2 Diabetes Mellitus (MODY) 11/2021 - 01/2010
11	Virus Diseases (Viral Diseases) 10/2021 - 03/2007
10	Pheochromocytoma 09/2022 - 06/2005
10	Thyroid Neoplasms (Thyroid Cancer) 08/2022 - 12/2011
10	Pneumonia (Pneumonitis) 01/2022 - 12/2005
10	Obesity 01/2022 - 01/2017
10	Colitis 01/2021 - 12/2007
9	Liver Diseases (Liver Disease) 03/2022 - 01/2010
9	Reperfusion Injury 01/2022 - 09/2015
9	Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome) 01/2022 - 02/2015
9	Infarction (Infarctions) 01/2022 - 12/2014
9	Spinal Cord Injuries (Spinal Cord Injury) 01/2022 - 04/2007
9	Adenocarcinoma of Lung 01/2022 - 01/2013
9	Lymphoma (Lymphomas) 10/2021 - 09/2004

Drug/Important Bio-Agent (IBA)

116	Proteins (Proteins, Gene)FDA Link 04/2022 - 05/2003
57	Pharmaceutical PreparationsIBA 12/2022 - 03/2004
48	Biomarkers (Surrogate Marker)IBA 08/2022 - 05/2004
35	Fluorodeoxyglucose F18 (Fludeoxyglucose F 18)FDA Link 01/2022 - 03/2008
33	Glucose (Dextrose)FDA LinkGeneric 11/2022 - 04/2007
32	CytokinesIBA 10/2022 - 06/2004
31	Biological ProductsIBA 01/2022 - 10/2007
30	MicroRNAs (MicroRNA)IBA 06/2022 - 08/2011
30	Messenger RNA (mRNA)IBA 01/2022 - 05/2004
25	Peptides (Polypeptides)IBA 01/2022 - 10/2007
22	Therapeutic UsesIBA 08/2022 - 12/2005
22	LipidsIBA 01/2022 - 06/2007
20	Antiviral Agents (Antivirals)IBA 01/2022 - 03/2007
20	Long Noncoding RNAIBA 01/2022 - 01/2014
17	Small Interfering RNA (siRNA)IBA 08/2022 - 11/2004
17	VaccinesIBA 01/2022 - 06/2004
17	RNA (Ribonucleic Acid)IBA 01/2022 - 05/2010
17	IntegrinsIBA 05/2020 - 09/2007
16	CXC ChemokinesIBA 06/2022 - 11/2002
16	DNA (Deoxyribonucleic Acid)IBA 01/2021 - 12/2006
15	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 08/2021 - 02/2003
13	EnzymesIBA 08/2022 - 07/2008
13	AntibodiesIBA 01/2022 - 10/2009
13	ChemokinesIBA 01/2022 - 10/2012
12	Insulin (Novolin)FDA Link 10/2022 - 05/2009
12	Oxygen (Dioxygen)IBA 03/2022 - 05/2012
12	LigandsIBA 07/2019 - 01/2005
11	Blood Glucose (Blood Sugar)IBA 10/2022 - 12/2011
11	Retinaldehyde (Retinal)IBA 08/2022 - 02/2015
11	Interleukin-6 (Interleukin 6)IBA 08/2022 - 06/2015
11	Transcription Factors (Transcription Factor)IBA 03/2022 - 12/2008
11	technetium Tc 99m hydrazinonicotinyl-Tyr(3)-octreotideIBA 02/2022 - 03/2009
11	Matrix Metalloproteinases (MMPs)IBA 01/2022 - 06/2007
11	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2022 - 02/2007
11	Paclitaxel (Taxol)FDA LinkGeneric 01/2021 - 04/2005
10	radix ophiopogonis drug combination radix ginseng fructus schizandrae (Shen Mai)IBA 01/2022 - 11/2015
10	Neuroprotective AgentsIBA 01/2022 - 01/2014
10	Somatostatin Receptors (Somatostatin Receptor)IBA 01/2021 - 10/2003
10	Caspase 3 (Caspase-3)IBA 08/2020 - 07/2011
10	Interleukin-8 (Interleukin 8)IBA 12/2019 - 10/2012
9	Hydrogen Sulfide (Sulfide, Hydrogen)IBA 04/2022 - 01/2015
9	Anti-Bacterial Agents (Antibiotics)IBA 12/2021 - 06/2008
9	Doxorubicin (Adriamycin)FDA LinkGeneric 11/2021 - 01/2016

Therapy/Procedure

143	Therapeutics 12/2022 - 04/2002
46	Drug Therapy (Chemotherapy) 12/2022 - 12/2003
29	Radiotherapy 01/2022 - 11/2004
17	Chinese Traditional Medicine (Traditional Chinese Medicine) 01/2022 - 05/2011
15	Aftercare (After-Treatment) 06/2022 - 10/2003
15	Immunotherapy 01/2022 - 06/2004
12	Transplantation 01/2022 - 02/2007